Fbw7a
WebFeb 12, 2009 · B, Fbw7a is a ubiquitin ligase that mono-ubiquitinates SRC-3 on serines 723 and 786 to superactivate SRC-3 and direct it preferentially to certain transcription factors, such as estrogen receptor (ER) and androgen receptor (AR). C, During each subsequent round of transcription, Fbw7a adds one more ubiquitin/round to the two sites. http://huanglab-rna.cn/wp-content/uploads/2024/04/paper-17.pdf
Fbw7a
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WebNational Center for Biotechnology Information WebDEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the progression of cell cycle S phase
WebDownload scientific diagram BLM Increases Fbw7a-Mediated K48-and K63-Linked c-Jun Ubiquitylation (A) Fbw7a-mediated in vitro ubiquitylation of c-Jun occur via mixed … WebDownload scientific diagram BLM turnover during mitosis depends on Fbw7α. (a) Synchronization of A-15 cells by double thymidine block. A-15 cells were subjected to double thymidine block and ...
WebThe present invention discloses an isolated nucleic acid molecule, comprising BLM gene or BLM gene derivative and an expression system directing over expression of the said … WebIn vitro c-Jun ubiquitylation reactions were carried out with non-radiolabeled in vitro transcribed and translated Fbw7a alone or Fbw7a in the presence of a range of …
WebUSP28 Cell proliferation MYC FBW7A 4 DNA damage response TP53BP1, claspin Unknown 3 USP44 Cell cycle regulation CDC20 Unknown 3 CYLD NF-κB signalling TRAF2, TRAF6 NEMO (IKBKG) 4 Cell proliferation BCL3 Unknown 4 UCHL1 Ubiquitin processing Ubiquitin precursors Unknown 1 UCHL5 (UCH37) Proteasomal degradation NFRKB …
WebThe cost to diagnose the P307A code is 1.0 hour of labor. The auto repair's diagnosis time and labor rates vary by location, vehicle's make and model, and even your engine type. … swedish clockWebkeywords = "c-Myc, CDK4, cell proliferation, FBW7a, gain of function, GOF, p53-R249S, phosphorylation, PIN1, ribosomal biogenesis, transcription", author = "Peng Liao and Zeng, {Shelya X.} and Xiang Zhou and Tianjian Chen and Fen Zhou and Bo Cao and Jung, {Ji Hoon} and {Del Sal}, Giannino and Shiwen Luo and Hua Lu", swedish clothing brand crossword clueWebApr 17, 2024 · Fbw7a is known as the major ubiquitin E3 ligase for nuclear SREBP-1c (nSREBP-1c) to promote its ubiquitination and degradation. 8 mTORC2 also induces … skyview baptist church facebookWebTranscription . Fbw7 and Usp28 Regulate Myc Protein Stability in skyview camera softwareWebDownload scientific diagram BLM is ubiquitylated by Fbw7α. (a–c) Degradation of BLM by Fbw7 depends on its N-terminal region, F-box and WD40 domain. U2OS cells were transfected with (a) Flag ... skyview calgary albertaWebFBW7 Antibody (A301-720A) in WB. Detection of human FBW7 by western blot. Samples: Whole cell lysate (25 µg) from My-La CD4+, HeLa, NCI-H1975, SU-DHL-1, and VLN3G2 … skyview cemetery pendleton oregonWebShipping Weight : 13 lb 6 oz. Weight of the product as it ships, including packaging. Shipping Dimensions : 23.5” x 9.7” x 11.3”. Dimensions of the product in inches, … skyview atlanta ferris wheel tickets