Ifn gamma cxcl10 induction
WebCXCL10, also known as IP-10, is a glutamic acid-leucine-arginine motif negative chemokine structurally and functionally related to MIG (CXCL9) and ITAC (CXCL11). CXCL10 is … Web9 mei 2011 · The chemokine interferon-γ inducible protein 10 kDa (CXCL10) is a member of the CXC chemokine family which binds to the CXCR3 receptor to exert its biological …
Ifn gamma cxcl10 induction
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Web29 jul. 2011 · C–X–C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the … Web23 okt. 2014 · CXCL10 (IP-10) is a small 10 kDa chemokine with antimicrobial activity. It is induced by IFN-γ, chemoattracts mononuclear cells, and promotes adhesion of T cells. Recently, we detected CXCL10 on the surface of the skin and in the oral cavity. In the current study, we used broth microdilution and radial diffusion assays to show that …
WebA critical event in the pathogenesis of EAE is the entry of both Ag-specific and Ag-nonspecific T lymphocytes into the CNS. In the present report, we investigated the role of … WebIP-10 (interferon-gamma inducible protein 10 kDa), also known as CXCL10, was originally identified as an IFN-γ-inducible gene. It is induced in a variety of cells in response to …
Web4 jan. 2024 · Keratinocytes produce a variety of inflammatory factors, such as macrophage inflammatory protein 3α (MIP-3α or CCL20), interferon γ–induced protein-10 (IP-10 or CXCL10), and intercellular adhesion molecule-1 (ICAM-1) to recruit T … Web27 jun. 2011 · CXCL10, interferon-gamma-inducible protein 10; GAPDH, glyceraldehyde-3-phosphate dehydrogenase. Induction of receptor activator of nuclear factor kappa-B …
Web21 mrt. 2024 · CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. Diseases associated with CXCL10 include Spotted Fever and Cryptosporidiosis. Among its related pathways are MIF Mediated …
WebC-X-C chemokine ligand 10 CXCL10, a main interferon (IFN)-γ inducible protein, now also recognized as a type I IFN inducible biomarker, plays a critical role in the pathogenesis and progression of several autoimmune diseases, including systemic sclerosis (SSc) [1,2] systemic lupus erythematosus (SLE) [], juvenile idiopathic arthritis (JIA) [] and … richard wensley 1829 - 1901WebCXCL10 together with CXCL9/monokine induced by IFN‐γ (MIG) and CXCL11/IFN‐inducible T cell α chemoattractant constitute the non‐ELR CXC chemokines, which all use CXCR3 as receptor . Given the strong activity of this receptor as mediator of T cell recruitment, expression of the non‐ELR CXC chemokines may be central for … redneck lounge chairWebTarget Information. IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response … richard wentland verona wiWebThe IP-10/CXCL10 expression level in IFN-γ-treated group was arbitrarily assigned a value of 100, and the data are presented as percentage reductions (*P<0.05 vs each IFN-γ … richard wenzel in south carolinaWeb20 jun. 2002 · Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C … redneck lowlife chopperWebDuring peak disease the levels of CXCL9 and CXCL10 mRNA and protein were increased significantly in the cerebellum and spinal cord but were reduced during the recovery … redneck lounge chair shopping cartWeb29 mrt. 2024 · Tat and IFN-gamma synergistically induce the expression of CXCL10, which is inhibited by MEK1/2 inhibitor and the p38 mitogen-activated protein kinase (MAPK) … richard wentworth making do and getting by