Myt1 cancer
WebAug 7, 2024 · The ubiquitin-proteasome system (UPS) is involved in multiple aspects of cellular processes, such as cell cycle progression, cellular differentiation, and survival (Davis RJ et al., Cancer Cell 26:455-64, 2014; Skaar JR et al., Nat Rev Drug Discov 13:889-903, 2014; Nakayama KI and Nakayama K, Nat Rev Cancer 6:369-81, 2006). F-box and WD repeat … http://www.tumorportal.org/view?geneSymbol=MYT1
Myt1 cancer
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WebApr 21, 2024 · Ovarian cancer is one of the most lethal gynecologic malignancies reported throughout the world. The initial, standard-of-care, adjuvant chemotherapy in epithelial … WebExpression of MYT1 (MTF1, MYTI, NZF2, PLPB1, ZC2H2C1, ZC2HC4A) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... To access cancer specific RNA and prognostic data, click on the cancer name. The cancer types are color-coded according to which type of normal organ the cancer originates ...
WebJun 20, 2024 · PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target. Author links open overlay panel Jianan Wang a 1, Lin Wang a 1, Saipeng Chen ... During interphase, Cdk1 accumulates in an inactive state, phosphorylated at inhibitory sites by Wee1/Myt1 kinases. At mitosis onset, Cdc25 phosphatase … WebApr 21, 2024 · Ovarian cancer is one of the most lethal gynecologic malignancies reported throughout the world. The initial, standard-of-care, adjuvant chemotherapy in epithelial ovarian cancer is usually a platinum drug, such as cisplatin or carboplatin, combined with a taxane. However, despite surgical removal of the tumor and initial high response rates to …
WebReena Beggs, Eddy S. Yang, in Advances in Protein Chemistry and Structural Biology, 2024. 4.2 Wee1. Wee1 is a tyrosine kinase that is known to be overexpressed in many cancer types such as luminal and HER2-positive breast cancer subtypes, hepatocellular carcinomas, and glioblastomas (Iorns et al., 2009).Wee1 directly interacts with histone H2B to halt histone … WebBackground and objective: We aimed to further study the role of Myelin Transcription Factor 1(MyT1) in tumor and other diseases and epigenetic regulation, and better understand the regulatory mechanism of MyT1. Methods: Using bioinformatics analysis, the structure and function of MyT1sequence were predicted and analyzed using bioinformatics analysis, …
WebDec 2, 2024 · In addition, Myt1 upregulation is associated with cancer cell metastasis and lower overall survival in colorectal cancers . Myt1 is also a crucial survival factor in a …
WebPatients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the … free template tailwind cssWebDec 1, 2024 · Downregulating Myt1 enhanced ectopic Cdk1 activity and restored sensitivity to adavosertib. These data demonstrate that upregulating Myt1 is a mechanism by which cancer cells acquire resistance to adavosertib. SIGNIFICANCE: Myt1 is a candidate … free template text after effectWebNCBI Description of MYT1: The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the … free templates with flower bordersWebOct 6, 2024 · Moreover, patients with breast cancer with high levels of MYT1 mRNA have worse prognosis, underscoring that MYT1 mRNA expression could be both a prognostic … farrow and ball discount code 2021Webalthough depletion of MYT1 alone did not affect long-term cell growth, it potentiated with DNA damage to inhibit cell growth in clonogenic survival and tumor xenograft models; … free template terms and conditionsWebJun 7, 2012 · WEE1 inhibition forces S-phase–arrested cancer cells into mitosis. A, assessment of the degree of synergy between gemcitabine and MK-1775 in 25 breast cell lines (23 breast cancer cell lines and 2 breast epithelial cell lines), displayed according to TP53 mutational status. Drug interactions are expressed as a CI. free templates to download and printWebMYT1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. free template thank you